Theodore C Pierson Selected Research

Flavivirus Infections

11/2021	Limited Flavivirus Cross-Reactive Antibody Responses Elicited by a Zika Virus Deoxyribonucleic Acid Vaccine Candidate in Humans.
1/2021	Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain.
12/2018	An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections.
11/2011	Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms.
6/2011	A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus.
3/2011	Antibody-mediated neutralization of flaviviruses: a reductionist view.
8/2010	Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin.
10/2009	Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus.
9/2008	Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development.
12/2007	Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner.

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Theodore C Pierson Research Topics

Disease

56	Infections 01/2022 - 04/2002
12	Virus Diseases (Viral Diseases) 01/2021 - 05/2004
10	Flavivirus Infections 11/2021 - 12/2007
8	Zika Virus Infection 01/2020 - 01/2016
8	West Nile Fever 01/2019 - 03/2005
5	Dengue (Dengue Fever) 11/2021 - 01/2011
3	Viremia 12/2019 - 06/2004
3	Japanese Encephalitis 01/2016 - 05/2005
3	Yellow Fever 01/2016 - 05/2005
2	Communicable Diseases (Infectious Diseases) 04/2021 - 12/2020
2	Coinfection 01/2018 - 11/2014
2	Alzheimer Disease (Alzheimer's Disease) 03/2004 - 05/2003
1	COVID-19 01/2021
1	Human Influenza (Influenza) 01/2020
1	Encephalitis (Encephalitis, Rasmussen) 12/2018
1	Vesicular Stomatitis 01/2018
1	Fetal Death 07/2017
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2017
1	Severe Dengue 12/2007
1	Body Weight (Weight, Body) 07/2005
1	St. Louis Encephalitis 05/2005

Drug/Important Bio-Agent (IBA)

25	VaccinesIBA 01/2022 - 05/2008
22	AntibodiesIBA 01/2022 - 03/2007
14	Neutralizing AntibodiesIBA 11/2021 - 05/2005
14	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2004
10	Monoclonal AntibodiesIBA 01/2019 - 03/2005
7	EpitopesIBA 01/2021 - 12/2006
5	Antiviral Agents (Antivirals)IBA 01/2021 - 07/2005
5	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 04/2002
4	Messenger RNA (mRNA)IBA 04/2021 - 01/2017
4	mRNA VaccinesIBA 10/2019 - 01/2017
3	Polysaccharides (Glycans)IBA 01/2019 - 12/2006
3	Complement System Proteins (Complement)IBA 11/2011 - 12/2007
3	Immunoglobulin G (IgG)IBA 10/2009 - 11/2007
3	IgG Receptors (Fc gamma RI)IBA 10/2009 - 12/2006
2	NucleosidesIBA 04/2021 - 12/2020
2	Lipid NanoparticlesIBA 04/2021 - 12/2020
2	DNA VaccinesIBA 12/2019 - 10/2019
2	Glycoproteins (Glycoprotein)IBA 01/2018 - 02/2006
2	RNA (Ribonucleic Acid)IBA 01/2017 - 01/2014
2	Small Interfering RNA (siRNA)IBA 12/2013 - 06/2005
1	Combined VaccinesIBA 11/2021
1	RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA 01/2021
1	Broadly Neutralizing AntibodiesIBA 01/2021
1	IronIBA 01/2021
1	SulfurIBA 01/2021
1	Hemagglutinins (Hemagglutinin)IBA 01/2020
1	LipidsIBA 10/2019
1	A-Form DNA (A-DNA)IBA 10/2019
1	AntigensIBA 10/2019
1	Interferon Type IIBA 01/2019
1	Heterophile AntibodiesIBA 11/2018
1	Explosive Agents (Explosives)IBA 01/2018
1	Viral RNAIBA 07/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	EnzymesIBA 01/2017
1	Histone MethyltransferasesIBA 01/2017
1	Blocking AntibodiesIBA 01/2017
1	3' Untranslated Regions (3' UTR)IBA 01/2017
1	Immune Sera (Antisera)IBA 09/2015
1	Fc Receptors (Fc Receptor)IBA 01/2014
1	AGRO 100IBA 12/2013
1	FurinIBA 11/2011
1	Opsonin Proteins (Opsonins)IBA 11/2011
1	MicroRNAs (MicroRNA)IBA 01/2011
1	LuciferasesIBA 01/2011
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 08/2010
1	AcidsIBA 07/2009
1	Immunoglobulin M (IgM)IBA 11/2007
1	Mannose (D-Mannose)IBA 12/2006
1	CarbohydratesIBA 02/2006
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 02/2006
1	LectinsIBA 02/2006
1	Glycoside Hydrolase InhibitorsIBA 07/2005
1	castanospermineIBA 07/2005
1	Interferon-betaIBA 03/2005
1	Enfuvirtide (Fuzeon)FDA Link 05/2004
1	TAK 779IBA 05/2004
1	Cadherins (E-Cadherin)IBA 03/2004
1	Amyloid (Amyloid Fibrils)IBA 03/2004
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 05/2003
1	Membrane Proteins (Integral Membrane Proteins)IBA 05/2003

Therapy/Procedure

5	Therapeutics 01/2021 - 03/2005
1	Highly Active Antiretroviral Therapy (HAART) 06/2004